What is AML?
Acute myeloid leukemia (AML) is a highly proliferative form of cancer where the bone marrow makes abnormal myeloblasts (a type of white blood cell). AML is the most common form of leukemia in adults, and will progress quickly if left untreated.
For information about AML and for patient support, please visit the following resources:
- American Cancer Society https://www.cancer.org/cancer/acute-myeloid-leukemia.html
- Cancer Care https://www.cancercare.org/diagnosis/leukemia
- Leukemia & Lymphoma Society http://www.lls.org/
AROG's ongoing clinical trials, please visit ClinicalTrials.gov
What is GIST?
Gastrointestinal stromal tumor (GIST) is a disease in which abnormal cells form in the tissues of the gastrointestinal tract: stomach, small intestine, and large intestine. GIST is the most common sarcoma of the gastrointestinal (GI) tract.
In approximately 5% of patients with GIST, defects in a gene called PDGFRα, known as D842V, lead to primary resistance to existing approved medications. Currently, there are no approved targeted therapy options for PDGFRα D842V mutant GIST.
Prior results have demonstrated the clinical safety and efficacy of crenolanib in patients with PDGFRα D842V mutant GIST
For more information about GIST and for patient support, please visit the following resources:
- GIST Support International http://www.gistsupport.org/about-gist
- Sarcoma Patients EuroNet (SPAEN) http://www.sarcoma-patients.eu/en/gist2
- Life Raft Group: https://liferaftgroup.org/
AROG's ongoing clinical trials, please visit ClinicalTrials.gov
